Endothelial function and carotid intima media thickness
Objective: this study aimed at assessing the endothelial function in patients with type 1 diabetes (t1dm) using flow-mediated dilation (fmd) response and carotid artery intima-media thickness (cimt. Hypertension, also known as high blood pressure, is a chronic medical condition, in which the blood pressure is elevated this is a common condition, which can lead to severe complications such as cardiovascular disease, heart attack, stroke and kidney disease, if not detected and treated early. Although carotid intima-media thickness is strongly associated with atherosclerosis, thickening of the intima-media may not always be due to atherosclerosis intima-medial thickening is a complex process, depending on a variety of factors, including blood pressure ,  local hemodynamics ,  shear stress  and circumferential tensile.
Carotid intima-media thickness and endothelial function: useful surrogate markers for establishing cardiovascular risk in patients with inflammatory rheumatic disease miguel a gonzalez-gay 1, 2 email author, carlos gonzalez-juanatey 3, tomas r vazquez-rodriguez 2. Metformin improves endothelial function and carotid intima media thickness in patients with pcos gynecological endocrinology: vol 31, no 5, pp 401-405 doi: 103109/0951359020151006188 metformin improves endothelial function and carotid intima media thickness in patients with pcos metformin improves endothelial function and. Relationship between endothelial dysfunction, carotid artery intima media thickness and circulating markers of vascular inflammation in obese hypertensive children and adolescents j pediatr endocrinol metab 200720: 1125 – 1136.
Carotid intima-media thickness (imt) methods—endothelium-dependent flow-mediated brachial artery dilation (fmd), endothelium-independent dilation response to glyceryl trinitrate (gtn), and carotid imt were assessed by high-resolution ultrasound in 118 healthy young. Function determined by digital reactive hyperemia peripheral arterial tonometry (rh-pat) and carotid artery intima- media thickness (imt) have both been proposed as surrogate markers for coronary. We investigated endothelial dysfunction, risk factors, and progression of carotid intima-media thickness (cimt) in late-middle-aged individuals at low to intermediate cardiovascular risk in a prospective study between 1997 and 2005. Juonala m, viikari js, laitinen t, marniemi j, helenius h, rönnemaa t et al interrelations between brachial endothelial function and carotid intima-media thickness in young adults: the cardiovascular risk in young finns study. Background detection of early vascular changes prior to clinical manifestations of atherosclerosis, such as increased arterial carotid intima-media thickness (cimt) and impaired endothelial function is of paramount importance for early identification of subjects at increased risk of accelerated atherosclerosis.
Read 1064-183 endothelial function and carotid intima-media thickness in young healthy subjects among endothelial nitric oxide synthase polymorphisms, journal of the american college of cardiology on deepdyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips. Endothelial function determined by digital reactive hyperemia peripheral arterial tonometry (rh-pat) and carotid artery intima-media thickness (imt) have both been proposed as surrogate markers for coronary artery disease (cad. Our findings in a group of middle-aged civil servants demonstrate, for the first time, that a noninvasive measure of endothelial function is associated with evidence of progression of carotid intima-media thickness over 6 years. Effect of pioglitazone compared with glimepiride on carotid intima-media thickness in type 2 diabetes and endothelial cell function 9–12 some of these beneficial effects may be independent of effects on glycemia 13–15 in animal models of atherosclerosis,. Carotid intima-media thickness decreased after 12 weeks in the after-school exercise group (p=0020) compared with the control group conclusions: this study provides preliminary evidence that a combined after-school exercise programme may.
We sought to evaluate the impact of er-niacin on carotid intima media thickness (cimt), endothelial function, and endothelial progenitor cell (epc) mobilization methods: carotid b-mode ultrasound was used to image the common and internal carotid arteries, at baseline and at 12 months after enrollment. We assessed carotid intima-media thickness (cimt), as a marker of atherosclerosis, and endothelial function in patients with hypothyroidism we included 70 female patients with hypothyroidism in the study, 40 patients with overt and 30 patients with subclinical hypothyroidism. To investigate sex differences associated with changes in brachial artery flow-mediated dilatation and carotid intima-media thickness by framingham risk score methods the study included 1083 patients aged 30 to 80 years. Background: decreases in endothelial function measured by reactive hyperemic index (rhi) correlated with increases in carotid intima-media thickness (cimt) in recently menopausal women with a low risk cardiovascular profile. The early cardiovascular damage was assessed with carotid intima-media thickness as a measure of subclinical atherosclerosis vs flow-mediated dilatation as a measure of endothelial function for both tests, we used continuous variables, considering that provide more information than the use of cut-off points.
Endothelial function and carotid intima media thickness
The ultrasound-based carotid intima-media thickness (imt) test is the most widely used imaging method to assess the level of early-stage carotid atherosclerosis however, research suggests that imt offers only minor improvement in cardiovascular disease risk prediction when added to the framingham risk score, a commonly used measure that takes. Endothelial function was measured by the flow-mediated vasodilatation of the brachial artery, as well as mean carotid artery intima-media thickness, and lipid profiles were studied at baseline and after 12 months of follow-up. Objectives we sought to examine the prognostic value of brachial artery (ba) flow-mediated vasodilation (fmd) and intima-media thickness (imt) in patients admitted for invasive evaluation of chest pain background both fmd and imt of the ba have been associated with coronary risk factors and the. The intima-media thickness (imt) of the carotid arteries was measured in the distal common carotid artery at a level 15 to 20 mm proximal to the carotid bulb the two bright echogenic lines in the arterial wall were identified as the intima and the media.
Background while both flow-mediated vasodilation (fmd) in the brachial artery (ba), which measures endothelium-dependent vasodilatation, and intima-media thickness (imt) in the carotid artery are correlated with the prognosis of coronary artery disease (cad), it is not clear which modality is a better predictor of cad. Arterial wall stress was associated with lumen diameter (r2 range, 052–083 p0001) and intima-media thickness (r2 range, 053–088 p0001) limited relationships were found among arterial wall layer thickness, stiffness, and endothelial function. It is commonly accepted that frequent tobacco exposure is associated with vascular endothelial injury and atherosclerotic diseases 1 in addition, both past and current passive smoking is related to endothelial dysfunction and deterioration of carotid intima-media thickness (cimt) and ankle-brachial index (abi) in adults 2, 3 passive smoking.
Vascular health measures included flow-mediated dilation (fmd) and carotid artery intima-media thickness (imt) cardiovascular measures included clinic and 24 hr bp levels, body composition, , and fasting glucose/cholesterol levels. Methods medline and embase were searched for articles comparing endothelial dysfunction (flow-mediated dilation, nitroglycerin-mediated dilation and peripheral arterial tonometry), vascular stiffness (stiffness index, pulse wave velocity) and carotid intima-media thickness (cimt) between patients and controls.